Theralase Releases Peer-Reviewed Research on Anti-Cancer Memory Response and Destruction of Cancerous Cells
Toronto, Ontario – June 24, 2014 Theralase Technologies Inc. (“Theralase”) (TSXV: TLT) (TLTFF: OTC Link®) announced today that it has publicly released two significant peer-reviewed research papers concerning the destruction of cancer.
The first paper demonstrates the vaccine and immune “memory response” effects of Theralase’s lead Photo Dynamic Compound (PDC), in the destruction of cancer in an animal model. The second paper demonstrates the effectiveness of Theralase’s anti-cancer technology in destroying both normoxic (normally oxygenated) cancerous cells and hypoxic (low oxygenated) cancerous cells.
Theralase’s Vaccine and Immune Memory Response:
Theralase’s research discovered that its lead Photo Dynamic Compound (PDC), intended for the destruction of cancer, demonstrated an ability to render animals immune to repeated exposures of the same cancer. At the 37th Annual American Society for Photobiology on June 16, 2014, in San Diego, California, this peer-reviewed research was presented via poster submission, entitled, “Elicitation of Tumor-free Long-term Survival and Long-lasting Antitumor Memory with Novel Non-immunosuppressive Near-Infrared PDT”
Theralase’s Destruction of Normal and Low Oxygenated Cancer Cells:
As cancerous tumors grow and advance in stage, they can develop areas of hypoxia and even hypoxic cores. These hypoxic areas and cores become resistant to treatment by ionizing radiation and other forms of treatment, including traditional Photo Dynamic Therapy (PDT). By developing state-of-the-art PDC technology that is able to destroy both normoxic and hypoxic cancerous cells, these findings strongly suggest the potential for future application of Theralase’s anti-cancer technology to a wide variety of cancers.
“Harnessing of novel visible and near-infrared light photoactivated, Type II/Type I, tunable, metal-based, small molecule, coordination complexes in PDT”, was presented at the conference and details how two additional Theralase PDCs were able to work in both normoxic and hypoxic conditions, strongly suggesting that these PDCs may be suitable in the treatment of more complex, solid core tumors that present with hypoxic areas or hypoxic cores, such as later stage or more developed cancers.
This research has been posted to Theralase’s corporate website at http://www.theralase.com/www2/
Dr. Arkady Mandel, Chief Scientific Officer of Theralase stated, “In the first presentation, Theralase’s preclinical trials prove that it is possible to generate a long-term anti-cancer memory response in animals. For the first time in our research program, we have demonstrated that Near Infrared (NIR) PDT leads to long standing clearance of colon cancer cells, but also provides long lasting protection against further tumour cell challenge in young (eight to ten weeks old) and older (ten to eleven month old) mice. This is the first step toward the long-term goal of developing an affordable and practical vaccine to prevent cancer recurrence. The next steps are to further validate this research with additional animals and different cancer cell lines and then translate this research into a human clinical trial. We are collaborating with experts in medical biophysics, immunology and clinical oncology from various internationally acclaimed clinical research institutes to further advance this remarkable platform technology. In the second presentation, Theralase demonstrates an ability of its PDC technology to effectively destroy both normoxic and hypoxic cancerous cells. This suggests an application of this technology to virtually all cancers, including later stage cancers that present with hypoxic areas and cores that can prove resistant to most forms of treatment.”
Roger Dumoulin-White, President and CEO of Theralase stated, “If our PDC technology is proven effective in cancer patients, through human clinical trials slated to commence in early 2015, the implications of this discovery are game changing for both Theralase and for the cancer patients affected. As demonstrated in the first research paper, the ability to destroy the original cancer and also program the body’s immune system to prevent its recurrence, after only a single treatment, is nothing short of miraculous. In the second research paper, demonstration of the ability to destroy virtually all types of cancers, whether normoxic or hypoxic in nature, opens up the potential of new treatment options for a wide range of cancers in various early and advanced stages.”
About Theralase Technologies Inc.
Theralase Technologies Inc. (“Theralase”) (TSXV: TLT) (TLTFF: OTC Link®) designs, manufactures and markets patented, superpulsed laser technology used in eliminating pain and destroying cancer. Theralase technology is safe and effective in eliminating pain, reducing inflammation and accelerating tissue regeneration in numerous nerve, muscle and joint conditions. Theralase is developing patented Photo Dynamic Compound (PDC) technology that is able to target and destroy cancers, bacteria and viruses when light activated.
Additional information is available at www.theralase.com and www.sedar.com
This press release contains forward-looking statements, which reflect the Company’s current expectations regarding future events. The forward-looking statements involve risks and uncertainties. Actual results could differ materially from those projected herein. The Company disclaims any obligation to update these forward-looking statements.
Neither TSX Venture Exchange nor its Regulation Services Provider (as that term is defined in the policies of the TSX Venture Exchanges) accepts responsibility for the adequacy or accuracy of this release.
For More Information:
Roger Dumoulin-White
President & CEO
1-866-THE-LASE (843-5273)
416-699-LASE (5273) ext. 225
rwhite@theralase.com
www.Theralase.com
Melony Jamieson – Get it Done
416-518-6355
melony@getitdone.ca