Theralase Discovers Anti-Cancer Drug Fluoresces in Tissue
Toronto, Ontario – May 14, 2015, Theralase Technologies Inc. (“Theralase” or the “Company”) (TLT:TSXV) (TLTFF: OTC Pink®), a leading biotechnology manufacturer focused on commercializing medical technologies to eliminate pain and destroy cancer, has discovered that its lead anti-cancer drug, TLD-1433, emits a fluorescent signature when light activated in a Non-Muscle Invasive Bladder Cancer (“NMIBC”) animal model.
The advantages of this discovery are three fold:
1) It can be used as a diagnostic tool for the oncologist to detect the presence of cancer cells and micro-metastases too small to be seen by the human eye.
2) It can be used to determine sufficient uptake of TLD-1433 into the cancer cells
3) After light activation, it can determine if the cancer cells that have absorbed the drug have been destroyed.
Theralase intends to use this new discovery in the treatment of NMIBC.
Clinical Treatment Protocol of NMBIC with Photo Dynamic Therapy:
- Intravesical installation of TLD-1433 into the bladder via cystoscope
- Allow approximately sixty minutes for the drug to diffuse into the bladder cancer cells
- Flush the bladder and refill with water
- Visual analysis by the uro-oncologist to check for fluorescence to indicate the presence of cancer cells, their specific location and whether sufficient quantities of the drug have been absorbed to proceed to light activation
- Light activation for approximately thirty minutes
- Post treatment analysis to check for no fluorescence indicating that all bladder cancer cells that absorbed the drug have been destroyed
Dr. Arkady Mandel, Chief Scientific Officer stated that, “TLD-1433-based fluorescence optical imaging technology represents an exciting opportunity in employing this technology to systematically detect and destroy cancer cells, improving the specificity of disease detection and treatment. The technology offers relative ease of integration into the operating room environment with instruments commonly used in a minimal invasive urological procedure. This technology holds promise to revolutionize our clinical paradigm in guiding medical procedures and can provide oncological surgeons and urologists with intraoperative capability to visualize and distinguish diseased from healthy tissue with cellular and molecular specificity.”
Roger Dumoulin-White, President and CEO stated, “Theralase continues to make ground breaking discoveries in our pursuit for the safe and effective treatment of cancer, commencing with NMIBC. The entire Theralase team looks forward to proving the safety, tolerability and efficacy of this technology in a Health Canada Phase Ib human clinical study.”
About Theralase Technologies Inc.
Theralase Technologies Inc. (“Theralase®”) (TSXV: TLT) (TLTFF: OTC Pink®) in its Therapeutic Laser Technology Division designs, manufactures and markets patented super-pulsed laser technology indicated for the: elimination of pain, reduction of inflammation and dramatic acceleration of tissue healing for numerous nerve, muscle and joint conditions. Theralase’s Photo Dynamic Therapy Division researches and develops specially designed molecules called Photo Dynamic Compounds, which are able to localize to the cancer cells and then when laser light activated, effectively destroy them.
Additional information is available at www.theralase.com and www.
Theralase Technologies Inc. was recognized as a TSX Venture 50® company in 2015. TSX Venture 50 is a trademark of TSX Inc. and is used under license.
This press release contains forward-looking statements, which reflect the Company’s current expectations regarding future events. The forward-looking statements involve risks and uncertainties. Actual results could differ materially from those projected herein. The Company disclaims any obligation to update these forward-looking statements.
Neither TSX Venture Exchange nor its Regulation Services Provider (as that term is defined in the policies of the TSX Venture Exchanges) accepts responsibility for the adequacy or accuracy of this release.
For More Information:
Roger Dumoulin-White
President & CEO, Theralase Technologies Inc.
1.866.THE.LASE (843-5273) ext. 225
416.699.LASE (5273) ext. 225
Chris
I understand how you feel; I harbored some resentment also.
With this type of company you have to be in for the long-haul
and you have to be intrigued by the story; I know I am.
This is actually one of the stocks I am “proud” to own.
Brian
Chris, I can understand your feeling about the financing this spring—it was probably not the best financing in the world. However, having been a urologist in my past life, I am extremely intrigued by their cancer project along with the high quality of medical people working with them. The report today just adds to my interest. What they’ve discussed is procedurally very important if it does what they are saying. It’ll be very positive to the urologist when he cytoscopes a patient with bladder cancer. Most of the time it is obvious to the eye of the urologist when he sees the cancer lesion that anatomically looks different to the normal mucosa of the bladder. The positive of the fluorescing tissue is that you may have tissue that is cancerous that appears not anatomically different then normal tissue—this tissue can then be removed whereas in the past it would be missed by the urologis during his cystoscopy. Having said that; as Brian said, I’m in it long term even though some of my shares are currently under water. I say this since what these gentlemen are doing is very intriguing and the possibilities very interesting. But you’re correct in you wondering about whether they could have done better with their recent financing.
I appreciate your comments! Hope to see you again this summer in YVR.
I re-read this a couple times, then I looked at volume.
Maybe this will be one of those extraordinary 3-day moves that results in a 50% pop.
This evening Theralase will appear on several “Day’s biggest gainers” list, we could see tremendous follow-though tomorrow when speculators will pile in.
This that want to sell for a break-even, may get their wish by the end of the week
I would have to say that I was pretty discouraged when the shares fell to Cdn$0.255. I discussed my concerns with Doc and Cory and was reminded by Doc that this particular investment’s success or failure will not be known until close to the final chapter.
I happen to agree with that comment.
Well, I sure hope they make it big, because that is the only way we share holders who bought before the financing this Spring will ever make good money. I plan to be out if it ever gets anywhere near the 50 cent option price.
The KER folks don’t agree, but I think it was really a screw job. As I posted before, the option part was obscene at best for the older share owners. Roger may know his cancer technology……..finance, not so much.